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Why an International Research Consortium?

Although there have been significant strides in CRPS research the last 20 years, there still is no solid information or RCTs on treatment or even definitive information about mechanisms and treatment responsive phenotype because:

  • CRPS is a relatively rare condition and treatment trials have generally been small N, single site pilot studies. Federal agencies that approve treatment (e.g., FDA in the US) and insurance payers do not consider preliminary, pilot, or case series type evidence. We need definitive trials.
  • Funding levels for basic and clinical research are at a historic lows.

Large, multi-site studies with appropriate levels are needed to advance research and the IRC will accomplish this through pooling of resources internationally for rapid and conclusive studies.